As seen for today in 2020, the never-ending research for the truth in laboratories for the cause, the roots, the bloody roots; the danger in the scientific project architecture has never been unveiled before so close for publicity.
Unisexual reproduction is widespread among lower vertebrates, but not in mammals. Deletion of the H19 imprinted region in immature oocytes produced bimaternal mice with defective growth; however, bipaternal reproduction has not been previously achieved in mammals. We found that cultured parthenogenetic and androgenetic haploid embryonic stem cells (haESCs) display DNA hypo-methylation resembling that of primordial germ cells. Through MII oocyte injection or sperm coinjection with hypomethylated haploid ESCs carrying specific imprinted region deletions, we obtained live bimaternal and bipaternal mice. Deletion of 3 imprinted regions in parthenogenetic haploid ESCs restorednormal growth of fertile bimaternal mice, whereas deletion of 7 imprinted regions in androgeneti chaploid ESCs enabled production of live bipaternal mice that died shortly after birth. Phenotypic analyses of organ and body size of these mice support the genetic conflict theory of genomic imprinting. Taken together, our results highlight the factors necessary for crossing same-sex reproduction barriers in mammals.Source: cell.com/cell-stem-cell/pdfExtended/S1934-5909(18)30441-7
I want to quote the most appealing element in the introduction again – “phenotypic analyses of organ and body size of these mice support the genetic conflict theory of genomic imprinting. Taken together, our results highlight the factors necessary for crossing same-sex reproduction barriers in mammals.“
After Dolly sheep, the scientific interest still struggles with animals and other genetic theories.
The history of Little Hanz and horse phobia was treated within correspondence. Well, the horse is also a beast then cherished mammal.
What goes around the Darwin Theory so now everything made in China.
“In January 2019, scientists in China reported the creation of five identical clonedgene-edited monkeys, using the same cloning technique that was used with Zhong Zhong and Hua Hua – the first ever cloned monkeys – and Dolly the sheep, and the same gene-editing Crispr–Cas9 technique allegedly used by He Jiankui in creating the first ever gene-modified human babies Lulu and Nana. The monkey clones were made in order to study several medical diseases.”Source: wikipedia.org